研究業績

　　　　　（2010年以降）

Yun YS, Noda S, Takahashi S, Takahashi Y, Inoue H. Piperine-like alkamides from Piper nigrum induce BDNF promoter and promote neurite outgrowth in Neuro-2a cells. J Nat Med. 2018 72, 238-245

Umemura M, Ogura T, Matsuzaki A, Nakano H, Takao K,Miyakawa T, Takahashi Y, Comprehensive Behavioral Analysis of Activating TranscriptionFactor 5-Deficient Mice.Front BehavNeurosci.2017, 11, 125.

Yun, Y.S., Tajima, M., Tahahashi, S., Takahashi, Y.,Umemura, M., Nakano, H., Park, H.S., and Inoue, H. Two alkaloids from bulbs of Lycoris sanguineaMAXIM. suppress PEPCK expression by inhibiting the phosphorylation of CREB.Phytother. Res. 30(10), 1689-1695. (2016).

Nakano H, Iida Y, Suzuki M, Aoki M, Umemura M,Takahashi S, Takahashi Y. Activating transcription factor 5 (ATF5) is essentialfor the maturation and survival of mouse basal vomeronasal sensory neurons. Cell Tissue Res. 2016, 363, 621-633..

Umemura M, Tsunematsu K, Shimizu YI, Nakano H, Takahashi S, Higashiura Y, Okabe M, Takahashi Y. Activating transcription factor 5isrequired for mouse olfactory bulb development via interneuron.　 Biosci Biotechnol Biochem. 2015 23, 1-8.

Yun YS, Fukaya H, Nakane T, Takano A, Takahashi S, Takahashi Y, Inoue H. A new bis-seco-abietane diterpenoid from HyptiscrenataPohl ex Benth. Org Lett. 2014 16, 6188-6191

Abe T., Kojima M., AkanumaS., Iwashita H., Yamazaki T., Okuyama R., Ichikawa K., Umemura M., Nakano H.,Takahashi S., Takahashi Y. N-terminal hydrophobic amino acids of ATF5confer IL-1b-induced stabilization,J Biol Chem, 289, 3888-3900 (2014)

Hatano M., Umemura M., Kimura N., Yamazaki T., Takeda H., Nakano H.,Takahashi S., Takahashi Y. The 5'-untranslated regionregulatesATF5 mRNAstability via nonsense-mediated mRNA decay in response to environmentalstress.FEBS J.280, 4693-4707 (2013)

Nakano H., Ymamada Y., Miyazawa T., Yoshida T. Gain-of-function screeningidentify miR-193a regulating proliferation and apoptosisinepithelial ovariancancer cells.Int. J. Oncol., 42, 1875-1882 (2013)

Lu J., Zhang S., Nakano H., Simmons D.G., Wang S., Kong S., Wang Q., Shen L.,Tu Z., Wang W., Wang B., Wang H., Wang Y., van Es J. H.,Clevers H., Leone G.,Cross J.C., Wang H. A positive feedback loop involving Gcm1 and Fzd5 directschorionic branching morphogenesisinthe placenta.PLOS Biol., 11, e1001536(2013)

Yoko-O T., Ichikawa D., Miyagishi Y., Kato A., Umemura M., Takase K., Ra M.,Ikeda K., Taguchi R., Jigami Y. Determinationandphysiological roles of theglycosylphosphatidylinositol lipid remodeling pathway in yeast.Mol Microbiol.,88, 140-155 (2013)

Goto, Y., Kajiwara, M., Yanagisawa, Y., Hirose, H., Yoshimi, T., Umemura, M.,Nakano, H., Takahashi, S., Shida, Y., Iguchi, T., Takahashi, Y.,Miura T. Detectionof vertebrate-type sterid hormones and their converting activity in theneogastropid, Thais clavigera.J. Mol. Studies, 78, 197–204 (2012)

Yun YS, Noda S, Shigemori G, Kuriyama R, Takahashi S, Umemura M, TakahashiY, Inoue H. Phenolic Diterpenes from RosemarySuppresscAMPResponsiveness of Gluconeogenic Gene Promoters.Phytother Res.DOI: 10.1002/ptr.4794 (2012)

Asanuma-Date K., Hirano Y., Le N., Sano K., Kawasaki N., Hashii N., Hiruta Y.,Nakayama K., Umemura M., Ishikawa K., Sakagami H.,Ogawa H. Functionalregulation of sugar assimilation by N-glycan-specific interaction of pancreatic a-Amylase with glycoproteinsofduodenal brush border membrane.J Biol Chem.,287, 23104-23118 (2012)

Haraguchi, T., Nakano H., Tagawa T., Ohki T., Ueno Y., Yoshida T., Iba H. Apotent 2’-O-methylated RNA-based microRNA inhibitorwithunique secondarystructures.Nucl. Acids Res., 40, e58 (2012).

Sagane, K., Umemura, M., Ogawa-Mitsuhashi, K., Tsukahara, K, Yoko-o, T.,Jigami, Y. Analysis of membrane topology and identificationofessentialresidues for the yeast endoplasmic reticulum inositol acyltransferase gwt1p.J.Biol.Chem., 286, 14649-14658 (2011).

Yamazaki, T., Ohmi, A., Kurumaya, H., Kato, K., Abe, T.,Yamamoto, H., Nakanishi, N., Okuyama, R., Umemura, M.,Kaise, T., Watanabe, R., Okawa, Y., Takahashi, S., Takahashi, Y.Regulation of the human CHOP gene promoterbythe stressresponse transcription factor ATF5 via the AARE1 site in humanhepatoma HepG2 cells.Life Sci.87,294-301 (2010).

Yoshimi, T., Hashimoto, F., Takahashi, S., Takahashi, Y.Suppression of embryonic lung branchingmorphogenesisbyantisense oligonucleotides against HOM/C homeobox factors.InVitro Cell Dev.Biol.Anim. 46, 664-672 (2010).

Nakano, H., Miyazawa, T., Kinoshita, K., Yamada, Y., Yoshida, T.Functional screening identifies a microRNA, miR-491 that inducesapoptosis by targeting Bcl-X(L) in colorectal cancer cells.Int.J.Cancer. 127, 1072-1080 (2010).

　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　　(2009年以前）