年度別

• 2012年
  • Ravishankar, B., H. Liu, R. Shinde, P. Chandler, B. Baban, M. Tanaka, D.H. Munn, A.L. Mellor, M.C. Karlsson, and T.L. McGaha. 2012.
    Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 109:3909-3914.
    
    
    
    
  • Mizukami, S., C. Kajiwara, M. Tanaka, T. Kaisho, and H. Udono. 2012.
    Differential MyD88/IRAK4 requirements for cross-priming and tumor rejection induced by heat shock protein 70-model antigen fusion protein. Cancer Sci 103:851-859
    
    
    
    
• 2011年
  • Muppidi, J.R., T.I. Arnon, Y. Bronevetsky, N. Veerapen, M. Tanaka, G.S. Besra, and J.G. Cyster. 2011.
    Cannabinoid receptor 2 positions and retains marginal zone B cells within the splenic marginal zone. J Exp Med 208:1941-1948.
    
    
    
  • Honke, N., N. Shaabani, G. Cadeddu, U.R. Sorg, D.E. Zhang, M. Trilling, K. Klingel, M. Sauter, R. Kandolf, N. Gailus, N. van Rooijen, C. Burkart, S.E. Baldus, M. Grusdat, M. Lohning, H. Hengel, K. Pfeffer, M. Tanaka, D. Haussinger, M. Recher, P.A. Lang, and K.S. Lang. 2011.
    Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nat Immunol 13:51-57.
    
    
    
  • Chow, A., D. Lucas, A. Hidalgo, S. Mendez-Ferrer, D. Hashimoto, C. Scheiermann, M. Battista, M. Leboeuf, C. Prophete, N. van Rooijen, M. Tanaka, M. Merad, and P.S. Frenette. 2011.
    Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J Exp Med 208:261-271.
    
    
    
    
  • Asano, K., A. Nabeyama, Y. Miyake, C.H. Qiu, A. Kurita, M. Tomura, O. Kanagawa, S. Fujii, and M. Tanaka. 2011.
    CD169-Positive Macrophages Dominate Antitumor Immunity by Crosspresenting Dead Cell-Associated Antigens. Immunity 34:85-95.
    
    
    
• 2010年
  • Tanaka, M., K. Asano, and C.H. Qiu. 2010. Immune regulation by apoptotic cell clearance. Ann N Y Acad Sci 1209:37-42.
    
    
    
  • Nabeyama, A., A. Kurita, K. Asano, Y. Miyake, T. Yasuda, I. Miura, G. Nishitai, S. Arakawa, S. Shimizu, S. Wakana, H. Yoshida, and M. Tanaka. 2010.
    xCT deficiency accelerates chemically induced tumorigenesis. Proc Natl Acad Sci U S A 107:6436-6441.
    
    
    
• 2009年
  • Tomura, M., Y.S. Mori, R. Watanabe, M. Tanaka, A. Miyawaki, and O. Kanagawa. 2009. Time-lapse observation of cellular function with fluorescent probe reveals novel CTL-target cell interactions. Int Immunol 21:1145-1150.
    
    
    
    
  • Qiu, C.H., Y. Miyake, H. Kaise, H. Kitamura, O. Ohara, and M. Tanaka. 2009.
    Novel subset of CD8{alpha}+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens. J Immunol 182:4127-4136.
    
    
    
• 2008年
  • Tanaka, M., Y. Miyake, and K. Asano. 2008. Maintenance of self-tolerance by apoptotic cell clearance. Front Biosci 13:6043-6049.
    
    
    
  • Witasp, E., W. Uthaisang, C. Elenstrom-Magnusson, R. Hanayama, M. Tanaka, S. Nagata, S. Orrenius, and B. Fadeel. 2007.
    Bridge over troubled water: milk fat globule epidermal growth factor 8 promotes human monocyte-derived macrophage clearance of non-blebbing phosphatidylserine-positive target cells. Cell Death Differ 14:1063-1065.
    
    
    
• 2007年
  • Tanaka, M., and Y. Miyake. 2007. Apoptotic cell clearance and autoimmune disorder. Curr Med Chem 14:2892-2897.
    
    
    
  • Miyake, Y., H. Kaise, K. Isono, H. Koseki, K. Kohno, and M. Tanaka. 2007.
    Protective Role of Macrophages in Noninflammatory Lung Injury Caused by Selective Ablation of Alveolar Epithelial Type II Cells. J Immunol 178:5001-5009.
    
    
    
  • Miyake, Y., K. Asano, H. Kaise, M. Uemura, M. Nakayama, and M. Tanaka. 2007.
    Critical role of macrophages in the marginal zone in the suppression of immune responses to apoptotic cell-associated antigens. J Clin Invest 117:2268-2278.
    
    
    
  • Hijikata, A., H. Kitamura, Y. Kimura, R. Yokoyama, Y. Aiba, Y. Bao, S. Fujita, K. Hase, S. Hori, Y. Ishii, O. Kanagawa, H. Kawamoto, K. Kawano, H. Koseki, M. Kubo, A. Kurita-Miki, T. Kurosaki, K. Masuda, M. Nakata, K. Oboki, H. Ohno, M. Okamoto, Y. Okayama, O.W. J, H. Saito, T. Saito, M. Sakuma, K. Sato, K. Sato, K. Seino, R. Setoguchi, Y. Tamura, M. Tanaka, M. Taniguchi, I. Taniuchi, A. Teng, T. Watanabe, H. Watarai, S. Yamasaki, and O. Ohara. 2007.
    Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics 23:2934-2941.
    
    
    
• 2006年
  • Nakaya, M., M. Tanaka, Y. Okabe, R. Hanayama, and S. Nagata. 2006. Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages. J Biol Chem 281:8836-8842.
    
    
    
• 2005年
  • Tanaka, M. 2005. Apoptotic cell clearance by phagocytes. International Congress Series 1285 55-59.
    
    
    
• 2004年
  • Miyasaka, K., R. Hanayama, M. Tanaka, and S. Nagata. 2004.
    Expression of milk fat globule epidermal growth factor 8 in immature dendritic cells for engulfment of apoptotic cells. Eur J Immunol 34:1414-1422.
    
    
    
  • Hanayama, R., M. Tanaka, K. Miyasaka, K. Aozasa, M. Koike, Y. Uchiyama, and S. Nagata. 2004.
    Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice. Science 304:1147-1150.
    
    
    
  • Hanayama, R., M. Tanaka, K. Miwa, and S. Nagata. 2004.
    Expression of Developmental Endothelial Locus-1 in a Subset of Macrophages for Engulfment of Apoptotic Cells. J Immunol 172:3876-3882.
    
    
    
  • Asano, K., M. Miwa, K. Miwa, R. Hanayama, H. Nagase, S. Nagata, and M. Tanaka. 2004.
    Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice. J Exp Med 200:459-467.
    
    
    
• 2003年
  • Tada, K., M. Tanaka, R. Hanayama, K. Miwa, A. Shinohara, A. Iwamatsu, and S. Nagata. 2003.
    Tethering of Apoptotic Cells to Phagocytes through Binding of CD47 to Src Homology 2 Domain-Bearing Protein Tyrosine Phosphatase Substrate-1. J Immunol 171:5718-5726.
    
    
    
  • Nagase, H., H. Fukuyama, M. Tanaka, K. Kawane, and S. Nagata. 2003.
    Mutually regulated expression of caspase-activated DNase and its inhibitor for apoptotic DNA fragmentation. Cell Death Differ 10:142-143.
    
    
    
• 2002年
  • Hanayama, R., M. Tanaka, K. Miwa, A. Shinohara, A. Iwamatsu, and S. Nagata. 2002. Identification of a factor that links apoptotic cells to phagocytes. Nature 417:182-187.
    
    
    
• 2001年
  • Shudo, K., K. Kinoshita, R. Imamura, H. Fan, K. Hasumoto, M. Tanaka, S. Nagata, and T. Suda. 2001.
    The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity. Eur J Immunol 31:2504-2511.
    
    
    
  • Itai, T., M. Tanaka, and S. Nagata. 2001.
    Processing of tumor necrosis factor by the membrane-bound TNF-alpha- converting enzyme, but not its truncated soluble form. Eur J Biochem 268:2074-2082.
    
    
    
• 2000年
  • McIlroy, D., M. Tanaka, H. Sakahira, H. Fukuyama, M. Suzuki, K. Yamamura, Y. Ohsawa, Y. Uchiyama, and S. Nagata. 2000.
    An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes. Genes Dev 14:549-558.
    
    
    
• 1999年
  • Tanaka, M., M.E. Fuentes, K. Yamaguchi, M.H. Durnin, S.A. Dalrymple, K.L. Hardy, and D.V. Goeddel. 1999.
    Embryonic lethality, liver degeneration, and impaired NF-kappaB activation in IKK-beta-deficient mice. Immunity 10:421-429.
    
    
    
  • Cao, Z., M. Tanaka, C. Regnier, M. Rothe, A. Yamit-hezi, J.D. Woronicz, M.E. Fuentes, M.H. Durnin, S.A. Dalrymple, and D.V. Goeddel. 1999.
    NF-kappa B activation by tumor necrosis factor and interleukin-1. Cold Spring Harb Symp Quant Biol 64:473-483.
    
    
    
• 1998年
  • Yagi, T., A. Sugimoto, M. Tanaka, S. Nagata, S. Yasuda, H. Yagita, T. Kuriyama, T. Takemori, and Y. Tsunetsugu-Yokota. 1998.
    Fas/FasL interaction is not involved in apoptosis of activated CD4+ T cells upon HIV-1 infection in vitro. J Acquir Immune Defic Syndr Hum Retrovirol 18:307-315.
    
    
    
  • Toyozaki, T., M. Hiroe, M. Tanaka, S. Nagata, H. Ohwada, and F. Marumo. 1998. Levels of soluble Fas ligand in myocarditis. Am J Cardiol 82:246-248.
    
    
    
  • Tanaka, M., T. Itai, M. Adachi, and S. Nagata. 1998. Downregulation of Fasligand by shedding. Nat Med 4:31-36.
    
    
    
  • Mizuki, M., S. Ueda, S. Tagawa, H. Shibayama, Y. Nishimori, M. Shibano, H. Asada, M. Tanaka, S. Nagata, U. Koudera, K. Suzuki, T. Machii, M. Ohsawa, K. Aozasa, T. Kitani, and Y. Kanakura. 1998.
    Natural killer cell-derived large granular lymphocyte lymphoma of lung developed in a patient with hypersensitivity to mosquito bites and reactivated Epstein-Barr virus infection. Am J Hematol 59:309-315.
    
    
    
  • Hashimoto, H., M. Tanaka, T. Suda, T. Tomita, K. Hayashida, E. Takeuchi, M. Kaneko, H. Takano, S. Nagata, and T. Ochi. 1998.
    Soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis. Arthritis Rheum 41:657-662.
    
    
    
  • Adachi, S., H. Ito, M. Tamamori, M. Tanaka, F. Marumo, and M. Hiroe. 1998.
    Skeletal and smooth muscle alpha-actin mRNA in endomyocardial biopsy samples of dilated cardiomyopathy patients. Life Sci 63:1779-1791.
    
    
    
• 1997年
  • Tanaka, M., T. Suda, T. Yatomi, N. Nakamura, and S. Nagata. 1997. Lethal effect of recombinant human Fas ligand in mice pretreated with Propionibacterium acnes. J Immunol 158:2303-2309.
    
    
    
  • Suda, T., H. Hashimoto, M. Tanaka, T. Ochi, and S. Nagata. 1997. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 186:2045-2050.
    
    
    
  • Ertel, W., M. Keel, R. Stocker, H.G. Imhof, M. Leist, U. Steckholzer, M. Tanaka, O. Trentz, and S. Nagata. 1997. Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury. J Neuroimmunol 80:93-96.
    
    
    
  • Bahr, G.M., A. Capron, J. Dewulf, S. Nagata, M. Tanaka, J.M. Bourez, and Y. Mouton. 1997. Elevated serum level of Fas ligand correlates with the asymptomatic stage of human immunodeficiency virus infection. Blood 90:896-898.
    
    
    
• 1996年
  • Tanaka, M., T. Suda, K. Haze, N. Nakamura, K. Sato, F. Kimura, K. Motoyoshi, M. Mizuki, S. Tagawa, S. Ohga, K. Hatake, A.H. Drummond, and S. Nagata. 1996. Fas ligand in human serum. Nat Med 2:317-322.
    
    
    
  • Takeda, K., Z.X. Yu, T. Nishikawa, M. Tanaka, S. Hosoda, V.J. Ferrans, and T. Kasajima. 1996. Apoptosis and DNA fragmentation in the bulbus cordis of the developing rat heart. J Mol Cell Cardiol 28:209-215.
    
    
    
  • Takahashi, T., M. Tanaka, J. Ogasawara, T. Suda, H. Murakami, and S. Nagata. 1996. Swapping between Fas and granulocyte colony-stimulating factor receptor. J Biol Chem 271:17555-17560.
    
    
    
  • Suda, T., M. Tanaka, K. Miwa, and S. Nagata. 1996. Apoptosis of mouse naive T cells induced by recombinant soluble Fas ligand and activation-induced resistance to Fas ligand. J Immunol 157:3918-3924.
    
    
    
  • Sato, K., F. Kimura, Y. Nakamura, H. Murakami, M. Yoshida, M. Tanaka, S. Nagata, Y. Kanatani, N. Wakimoto, N. Nagata, and K. Motoyoshi. 1996. An aggressive nasal lymphoma accompanied by high levels of soluble Fas ligand. Br J Haematol 94:379-382.
    
    
    
  • Ito, H., S. Adachi, M. Tamamori, H. Fujisaki, M. Tanaka, M. Lin, H. Akimoto, F. Marumo, and M. Hiroe. 1996. Mild hypoxia induces hypertrophy of cultured neonatal rat cardiomyocytes: a possible endogenous endothelin-1-mediated mechanism. J Mol Cell Cardiol 28:1271-1277.
    
    
    
  • Estaquier, J., M. Tanaka, T. Suda, S. Nagata, P. Golstein, and J.C. Ameisen. 1996. Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists. Blood 87:4959-4966.
    
    
    
  • Akimoto, H., H. Ito, M. Tanaka, S. Adachi, M. Hata, M. Lin, H. Fujisaki, F. Marumo, and M. Hiroe. 1996. Heparin and heparan sulfate block angiotensin II-induced hypertrophy in cultured neonatal rat cardiomyocytes. A possible role of intrinsic heparin-like molecules in regulation of cardiomyocyte hypertrophy. Circulation 93:810-816.
    
    
    
• 1995年
  • Tanaka, M., T. Suda, T. Takahashi, and S. Nagata. 1995. Expression of the functional soluble form of human fas ligand in activated lymphocytes. Embo J 14:1129-1135.
    
    
    
  • Tanaka, M., M. Hiroe, H. Ito, T. Nishikawa, S. Adachi, K. Aonuma, and F. Marumo. 1995. Differential localization of atrial natriuretic peptide and skeletal alpha-actin messenger RNAs in left ventricular myocytes of patients with dilated cardiomyopathy. J Am Coll Cardiol 26:85-92.
    
    
    
  • Fujisaki, H., H. Ito, Y. Hirata, M. Tanaka, M. Hata, M. Lin, S. Adachi, H. Akimoto, F. Marumo, and M. Hiroe. 1995. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J Clin Invest 96:1059-1065.
    
    
    
  • Adachi, S., H. Ito, Y. Ohta, M. Tanaka, S. Ishiyama, M. Nagata, T. Toyozaki, Y. Hirata, F. Marumo, and M. Hiroe. 1995. Distribution of mRNAs for natriuretic peptides in RV hypertrophy after pulmonary arterial banding. Am J Physiol 268:H162-169.
    
    
    
• 1994年
  • Tanaka, M., H. Ito, S. Adachi, H. Akimoto, T. Nishikawa, T. Kasajima, F. Marumo, and M. Hiroe. 1994. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 75:426-433.
    
    
    
  • Tanaka, M., M. Hiroe, T. Nishikawa, T. Sato, and F. Marumo. 1994. Cellular localization and structural characterization of natriuretic peptide-expressing ventricular myocytes from patients with dilated cardiomyopathy. J Histochem Cytochem 42:1207-1214.
    
    
    
  • Takahashi, T., M. Tanaka, J. Inazawa, T. Abe, T. Suda, and S. Nagata. 1994. Human Fas ligand: gene structure, chromosomal location and species specificity. Int Immunol 6:1567-1574.
    
    
    
  • Takahashi, T., M. Tanaka, C.I. Brannan, N.A. Jenkins, N.G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976.
    
    
    
  • Adachi, S., H. Ito, H. Akimoto, M. Tanaka, H. Fujisaki, F. Marumo, and M. Hiroe. 1994. Insulin-like growth factor-II induces hypertrophy with increased expression of muscle specific genes in cultured rat cardiomyocytes. J Mol Cell Cardiol 26:789-795.
    
    
    
• 1993年
  • Kawai, M., T. Nishikawa, M. Tanaka, A. Ando, T. Kasajima, T. Higa, T. Tanikawa, M. Kagawa, and K. Momma. 1993. An autopsied case of Williams syndrome complicated by moyamoya disease. Acta Paediatr Jpn 35:63-67.
    
    
    
  • Ito, H., Y. Hirata, S. Adachi, M. Tanaka, M. Tsujino, A. Koike, A. Nogami, F. Murumo, and M. Hiroe. 1993. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 92:398-403.
    
    
    

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